解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::In the period 1967-1981, 102 patients older than 70 years were treated for a colorectal carcinoma. The mean age was 76 years. The average delay was 7.6 months. Obstruction as initial symptom was seen in only 8% of the cases. The resection rate was 85%. The postoperative mortality rate was 6% for patients patients who ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.6.321
更新日期:1985-11-01 00:00:00
abstract::Tests of intestinal permeability are used as a reflection of upper-small-intestinal mucosal damage. Thirty-two elderly in-patients aged 75-96 years, and 64 hospital volunteers aged 22-64 years with no overt gastro-intestinal disease were studied to determine whether permeability changes with increasing age. Intestinal...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.5.312
更新日期:1985-09-01 00:00:00
abstract::A retrospective study was performed of 163 patients aged 65 years and over with a diagnosis of duodenal ulceration admitted to one Health District over a period of six years. Eighty per cent of the patients were admitted with acute complications, 50% bled and 30% were perforated. A large proportion of these patients w...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.4.225
更新日期:1985-07-01 00:00:00
abstract::From an international comparison of arm anthropometric reference norms for the elderly a new diagnostic criterion for severe wasting malnutrition was derived: corrected arm muscle area at or below 16.0 cm2 for men or 16.9 cm2 for women. Of 201 consecutive hospital admissions aged 65 years and over, 10 subjects were ma...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.3.149
更新日期:1985-05-01 00:00:00
abstract::Doppler-shifted ultrasound and spectral analysis were used to assess signals from the resting supra-orbital artery and the common carotid artery at the base of the neck of 658 (270 male, 388 female) asymptomatic subjects aged 5 to 90 years. The sonagrams obtained showed two peaks (A and B) during cardiac systole. The ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/14.2.102
更新日期:1985-03-01 00:00:00
abstract::From December 1982 to August 1983, a total of 242 oesophago-gastro-duodenoscopies were performed for 208 elderly patients in the Geriatric Unit, Princess Margaret Hospital, Hong Kong. These were done as part of an investigatory procedure in the Geriatric Unit, the first of its kind in Hong Kong. In the 9-month survey,...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/13.5.285
更新日期:1984-09-01 00:00:00
abstract::In a city where specialist homes for the elderly mentally infirm (EMI) have been extensively developed, a study was carried out to determine if residents in such homes were mentally impaired to a degree intermediate between that of residents in ordinary homes, and those in psychogeriatric beds. The study, using valid ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/13.4.218
更新日期:1984-07-01 00:00:00
abstract::This paper is an exploratory attempt to examine international differences in the proportion of old people living in non-private households. The aim of the study was to provoke further discussion of the role which institutions play in the care of the elderly in various settings and to examine the effect of certain demo...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/13.3.129
更新日期:1984-05-01 00:00:00
abstract::Investigation of 21 elderly women with a wide range of renal function showed that plasma creatinine concentrations above 100 mumol/l were associated with glomerular filtration rates (GFR) below 50 ml/min. Plasma 1,25-dihydroxyvitamin D concentrations and radio-calcium absorption were directly related to GFR and were l...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/13.1.14
更新日期:1984-01-01 00:00:00
abstract::There have so far been no reported studies of localization of urinary tract infection (UTI) in elderly women. The site of infection, renal or bladder, in significant urinary tract infection in 50 elderly women (mean age 80) admitted acutely to a geriatric unit was determined by the Fairley bladder washout method. Of t...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/12.4.317
更新日期:1983-11-01 00:00:00
abstract::High rates of mortality are an abiding feature of homes for the elderly. Almost a fifth (19.2%) of a cohort of 6947 residents died in the 12 months following initial assessment. Survival rates vary widely, however, for different groups within the residential population. Using data from a longitudinal study of 175 home...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/12.3.240
更新日期:1983-08-01 00:00:00
abstract::Muscle cramps are painful and common in elderly patients but have largely escaped medical investigation. Quinine sulphate is usually the sole drug prescribed, even though firm evidence for its efficacy is not available. The results of the present double-blind cross-over study show that quinine was significantly superi...
journal_title:Age and ageing
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ageing/12.2.155
更新日期:1983-05-01 00:00:00
abstract::A straight abdominal radiograph can be used in the elderly to indicate a loaded colon. Two groups of patients were identified using radiology, one with faeces-filled caeca and the other with gas-filled caeca. Gastro-intestinal transit time measurements and breath methane analysis, an indicator of colonic bacterial act...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/12.2.105
更新日期:1983-05-01 00:00:00
abstract::Digoxin elimination phase kinetics have been studied in 24 hospital in-patients (mean age 79 years), six of whom showed no evidence of digoxin toxicity. The others, with suspected toxicity, have been grouped according to the nature of the drug effects observed. Renal function, digoxin elimination half-life, apparent v...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/12.1.29
更新日期:1983-02-01 00:00:00
abstract::Within the wide range of topics embraced in the subject of geriatric medicine, a division may be made as far as teaching is concerned into: 1. those that could be taught by other people; 2. those that should be taught by other people; 3. those that cannot be taught by other people. If attitudes throughout the medical ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::In a study of two representative population samples of 70-year-olds, one of which was followed up at 75 years of age, digitalis treatment was associated with oestrogen-like metabolic effects, indicated by changes in the composition of the plasma phospholipid fraction. Digitalis treatment, at least at these ages, is re...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.4.261
更新日期:1982-11-01 00:00:00
abstract::Studies in the United States have suggested that medical students' bias against older patients is not influenced by ad hoc courses in geriatrics. If the suggestion is correct then there should be no difference between the attitudes towards the care of the aged and to a career with elderly patients among students attac...
journal_title:Age and ageing
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ageing/11.3.196
更新日期:1982-08-01 00:00:00
abstract::Among 352 residents of a home for the elderly, who were fully mobile and devoid of most predisposing factors for bacteriuria, 19% of men and 27% of women had two positive cultures within two months. Positive conversion at one year among men and women negative at entry was 11% and 23% respectively, negative conversion ...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.3.169
更新日期:1982-08-01 00:00:00
abstract::An assessment of thiamine status was made in two groups of elderly orthopaedic patients. None of the 30 men and women presenting for elective total hip replacement was malnourished before operation but there was a significant fall in the thiamine status 48 hours later, which had returned to normal by 14 days. In contr...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.2.101
更新日期:1982-05-01 00:00:00
abstract::In the population study Seventy-year-old People in Göteborg, 449 70-year-old men were examined in 1971/72. Out of these, 331 were re-examined in 1976/77 at age 75, together with a cohort-comparison group of 474 70-year-old men. Cohort differences and a lower smoking prevalence at higher ages were observed. The loss of...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.1.45
更新日期:1982-02-01 00:00:00
abstract::Sway has been measured by Wright's Ataxiameter in 151 frail elderly and five young subjects, and compared with various sensory modalities. There is a close relationship between increased sway and impaired vibration sense in the legs. No correlations emerged with proprioception but this may reflect the imprecision of t...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/11.1.1
更新日期:1982-02-01 00:00:00
abstract::Ejection fraction was measured directly by a radionuclide method, and indirectly from systolic time intervals, in elderly patients in atrial fibrillation. Both methods show that the ejection fraction averages approximately 55% at mean ventricular rates of 50-70 beats/min and falls to 20% or below as mean rate increase...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/10.4.231
更新日期:1981-11-01 00:00:00
abstract::In a survey of all 2069 in-patients at 14 geriatric centres, 249 patients were found to have received drugs for the treatment of parkinsonism. There was a wide variation in point prevalence which varied from 4.6% to 22.6% between centres. Levodopa, usually in combination with a decarboxylase inhibitor, was the most fr...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/10.2.81
更新日期:1981-05-01 00:00:00
abstract::The effectiveness was compared of 'Classroom' Reality Orientation presented (1) once daily, in groups; (2) twice daily, in groups; and (3) once daily, individually. On a questionnaire measure of orientation all three versions produced significantly greater improvement than that found in an untreated control group, but...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/10.1.33
更新日期:1981-02-01 00:00:00
abstract::Plasma and red-cell folate levels and dietary folate intake were monitored for about six months, including two months during which supplementary vitamin C was given, in 21 healthy elderly men and women living at home in the north of England. Although biochemical values were consistently low in some subjects, no clinic...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/9.4.241
更新日期:1980-11-01 00:00:00
abstract::Fasting serum cholesterol and triglyceride levels, and lipoprotein electrophoretic patterns have been investigated in 42 men aged 67-92 years (mean 79 years). Although all the cholesterol and the majority of the triglyceride levels were within the normal range for younger people, both were significantly greater (P < 0...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/9.3.154
更新日期:1980-08-01 00:00:00
abstract::Two studies of the social behaviour of geriatric patients are reported. In the first, lunchtime observations were made of two comparable wards in a continuing-care hospital and all episodes of social interaction recorded. There were twice as many interactions on one ward as on the other and their type and variety diff...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/9.2.93
更新日期:1980-05-01 00:00:00
abstract::Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons c...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/8.2.86
更新日期:1979-05-01 00:00:00
abstract::An outline is given of simple urodynamic investigations applicable to elderly subjects. The type of patient presenting primarily to geriatric departments with urinary incontinence, whose management is aided by such studies, is described under various clinical groupings. The requirement for urodynamic studies and the b...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/8.1.41
更新日期:1979-02-01 00:00:00
abstract::The plasma concentration of beta-thromboglobulin was estimated in elderly in-patients using a radio-immuno-assay technique. There were highly significance differences between the mean values of patients with arterial or venous thrombosis, as compared with controls. The ability of the test to detect thrombosis above th...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/8.1.13
更新日期:1979-02-01 00:00:00
abstract::The disproportionately high suicide rate among the elderly is examined in this review. As opposed to younger age groups, a close association exists between suicide and parasuicide in old age. Factors associated with these events include a high incidence of depression, serious physical illness, as well as social factor...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/7.4.201
更新日期:1978-11-01 00:00:00
abstract::Capillary fragility has been examined in 110 elderly patients, excluding those patients who might have been expected to have abnormal fragility. Nonetheless, fragility appeared to be greater in elderly patients than in younger subjects. It was much increased in the non-paralysed arm of hemiplegic patients but not in t...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/7.2.96
更新日期:1978-05-01 00:00:00
abstract::A study is reported of the religious beliefs, attitudes, and practice of old people in the West of Scotland, based on a questionnaire given to 501 people aged 65 years and over randomly selected from those living at home. Almost all had had a full range of religious instruction, and regarded their parents as religious...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/7.1.40
更新日期:1978-02-01 00:00:00
abstract::From a study of routine electrocardiography on 300 ill elderly patients in an acute geriatric unit, it is evident that the incidence of atrial fibrillation, ventricular extrasystoles, myocardial ischaemia and myocardial infarction is much higher than in the general population of similar age group. In females, the inci...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/6.3.163
更新日期:1977-08-01 00:00:00
abstract::A double-blind, placebo-controlled, clinical study was performed to assess the effects of oral betahistine hydrochloride (Serc) on mental impairment and physical disability in patients with established cerebrovascular disease. Fifty-three patients were admitted to the study during 18 months. Forty-five patients comple...
journal_title:Age and ageing
pub_type: 临床试验,杂志文章
doi:10.1093/ageing/6.3.179
更新日期:1977-08-01 00:00:00
abstract::Genetic factors are known to be of importance in determining the rate of biotransformation of foreign compounds in the liver. Adverse reactions to drugs are increased and pharmacokinetic parameters altered with age. In the present study, the effect of age on plasma paroxonase activity is studied. Paroxonase is a hepat...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/6.2.89
更新日期:1977-05-01 00:00:00
abstract::The effects of discontinuing long-term diuretic therapy were investigated by means of a double-blind randomized controlled trial. A total of 141 elderly patients in the long-stay wards of six hospitals were found to be taking maintenance diuretics, and for 33 of these the drugs were judged to be mandatory. Of the rema...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/6.1.38
更新日期:1977-02-01 00:00:00
abstract::Clinical assessments have to be used in epidemiological studies in the absence of more objective means of establishing diagnosis or recording events in the natural history of disease. This requires the standardization of definition, technique and interpretation as a means of reducing observer variability in clinical e...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.4.233
更新日期:1976-11-01 00:00:00
abstract::In one experiment, four groups of six-week-old-male PVG rats were, respectively, given tap water ('control group'), 0.00125M, 0.0025M, and 0.005M lathyrogen (aminoacetonitrile hydrochloride: AAN) solutions ad libitum for a period of 20 weeks. In a second experiment, 12-week-old male rats were similarly treated. It was...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.3.155
更新日期:1976-08-01 00:00:00
abstract::The elastic and mechanical behaviour of isolated papillar muscle was studied in aged and in young rats. The spontaneous fall in tension (stress relaxation phenomenon) and the duration of the active state of the contractile element during the isometric and isotonic contraction were greater in aged than in young rats. T...
journal_title:Age and ageing
pub_type: 杂志文章
doi:10.1093/ageing/5.2.71
更新日期:1976-05-01 00:00:00